{"title":"Glutathione","description":"\u003ch2\u003eBuy glutathione: an endogenous substance as a supplement\u003c\/h2\u003e\n\u003cp\u003eGlutathione is a substance that occurs naturally in the body and is present in virtually all cells. It is composed of three amino acids (cysteine, glutamic acid, and glycine) and is therefore called a tripeptide. As a supplement, glutathione is popular, including in a liposomal form aimed at absorption and in combination with substances such as NAC and milk thistle (silymarin).\u003c\/p\u003e\n\u003cp\u003eIn our range, you will find glutathione in various forms and from multiple brands. For example, there is standalone L-glutathione 500 mg in capsules from Vit4ever, liposomal glutathione 500 mg from Osavi, and a combination preparation from Osavi with silymarin, NAC, and LOLA. This allows you to choose between pure glutathione and a complex with multiple substances, in varying dosages.\u003c\/p\u003e\n\u003ch3\u003eWhat is glutathione?\u003c\/h3\u003e\n\u003cp\u003eGlutathione is a tripeptide, a small molecule composed of the amino acids cysteine, glutamic acid, and glycine. It occurs naturally in the body and is present in virtually all cells. There are two forms: the reduced form (indicated as GSH or reduced glutathione) and the oxidized form. Supplements usually contain the reduced form, often indicated as L-glutathione. The label states how much glutathione a product provides per serving and which form it is.\u003c\/p\u003e\n\u003ch3\u003eWhat does the body make glutathione from and where is it found?\u003c\/h3\u003e\n\u003cp\u003eThe body produces glutathione itself from three amino acids: cysteine, glutamic acid, and glycine. Cysteine is often considered the building block that is least readily available. The amino acids that serve as building blocks are found in high-protein foods, such as meat, fish, eggs, dairy, legumes, and nuts. Glutathione itself is also found in small amounts in fresh fruits and vegetables. In the body, glutathione is present in virtually all cells. As a supplement, it is offered alone or in combination with other substances.\u003c\/p\u003e\n\u003ch3\u003eWhat forms of glutathione are there?\u003c\/h3\u003e\n\u003cp\u003eGlutathione is offered in various forms. The reduced form (GSH or L-glutathione) is the form you most often encounter in capsules. In addition, there is liposomal glutathione, where the glutathione is packaged in small fat globules (liposomes), a technique aimed at absorption. You will also come across S-acetyl-glutathione, a variant with an acetyl group. The forms differ in composition and presentation; on the label, you can read which form and quantity a specific product provides.\u003c\/p\u003e\n\u003ch3\u003eIs glutathione the same as L-glutamine?\u003c\/h3\u003e\n\u003cp\u003eGlutathione is sometimes confused with L-glutamine, but they are two different substances. L-glutamine is a single amino acid that is mainly known among athletes and in sports nutrition. Glutathione is a tripeptide composed of three amino acids (including glutamic acid, which is related to glutamine, but not the same). The names are similar, but the substances, their composition, and their application differ. Therefore, pay close attention when choosing whether you are looking for glutathione or L-glutamine.\u003c\/p\u003e\n\u003ch3\u003eWhat is the difference between glutathione and NAC?\u003c\/h3\u003e\n\u003cp\u003eGlutathione and NAC (N-acetylcysteine) are often mentioned in the same breath, but they are different substances. NAC is a form of the amino acid cysteine, one of the three building blocks of glutathione. Glutathione itself is the complete tripeptide of cysteine, glutamic acid, and glycine. In supplements, you will find them separately, but also together in one preparation, such as the combination product from Osavi with glutathione, NAC, silymarin, and LOLA. Those looking for pure glutathione choose a standalone or liposomal product; those who want to combine multiple substances look for a complex.\u003c\/p\u003e\n\u003ch3\u003eLiposomal glutathione and absorption\u003c\/h3\u003e\n\u003cp\u003eOne consideration with glutathione is absorption, because the molecule is partially broken down in the digestive system. For that reason, glutathione is often offered in a liposomal form: the glutathione is then packaged in small fat globules (liposomes), a technique aimed at absorption. Osavi's liposomal glutathione uses the branded raw material Liposovit®-Glutathione for this purpose. When comparing products, it is useful to pay attention to the form (for example, liposomal or standard capsules), the amount of glutathione per serving, and whether a standardized raw material is used.\u003c\/p\u003e\n\u003ch3\u003eGlutathione combined with NAC and milk thistle\u003c\/h3\u003e\n\u003cp\u003eGlutathione is regularly combined with other substances in supplements. A well-known combination is with NAC (N-acetylcysteine), a form of the amino acid cysteine, which is one of the building blocks of glutathione. You will also come across glutathione in complexes with milk thistle (silymarin) and with amino acids such as L-ornithine-L-aspartate (LOLA). The combination preparation from Osavi in our range brings glutathione, silymarin, NAC, and LOLA together in one capsule. These complexes are intended for those who want to use multiple substances at the same time; those looking for pure glutathione choose a standalone or liposomal product.\u003c\/p\u003e\n\u003ch3\u003eWhen do you take glutathione?\u003c\/h3\u003e\n\u003cp\u003eThere is no fixed time that applies to everyone; the time of use varies per product and per person. Many people take glutathione at a time that fits into their daily routine, for example with a meal or on an empty stomach, depending on what the manufacturer indicates. The packaging states how many capsules or servings per day are intended and at what time. Follow the directions for use of the specific supplement you use.\u003c\/p\u003e\n\u003ch3\u003eHow much glutathione per day?\u003c\/h3\u003e\n\u003cp\u003eNo official recommended daily amount has been established for glutathione. The dosage per product varies and is stated on the packaging, expressed in milligrams per capsule or serving, for example 500 mg. The liposomal glutathione and the standalone L-glutathione in our range each provide 500 mg per indicated serving. Follow the directions for use of the specific supplement and do not exceed the recommended dosage without advice. If you are taking medication, during pregnancy or breastfeeding, or in case of doubt, it is wise to consult a doctor or therapist beforehand.\u003c\/p\u003e\n\u003ch3\u003eWho is glutathione intended for?\u003c\/h3\u003e\n\u003cp\u003eGlutathione is chosen by people who want to use this endogenous substance as a standalone supplement or in combination with substances such as NAC and milk thistle. Because it is an endogenous substance, you can use it as a standalone supplement or as part of a broader complex. Most glutathione supplements in capsule form are suitable for vegetarians and vegans; always check this and any allergens on the label. Glutathione is a dietary supplement and not a replacement for a varied diet.\u003c\/p\u003e\n\u003ch3\u003eBuying glutathione: what to pay attention to?\u003c\/h3\u003e\n\u003cp\u003eWhen choosing a glutathione supplement, there are a few points that are practically useful to pay attention to. Look at the amount of glutathione per serving and at the form: liposomal glutathione or a branded raw material such as Liposovit® is aimed at absorption. Determine whether you are looking for pure glutathione or a combination, for example with NAC or milk thistle. Pay attention to whether it is the reduced form, to the purity, to certification marks such as vegan, and to the price per daily serving.\u003c\/p\u003e\n\u003cp\u003eGlutathione is an endogenous tripeptide. For related products, also view our collections \u003ca href=\"\/en\/collections\/antioxidanten\"\u003eAntioxidants\u003c\/a\u003e, \u003ca href=\"\/en\/collections\/aminozuren\"\u003eAmino Acids\u003c\/a\u003e, \u003ca href=\"\/en\/collections\/nac\"\u003eNAC\u003c\/a\u003e, and \u003ca href=\"\/en\/collections\/mariadistel\"\u003eMilk Thistle\u003c\/a\u003e.\u003c\/p\u003e","products":[{"product_id":"l-glutathion-vit4ever","title":"L-Glutathione 500mg | 120 Capsules | Vit4ever","description":"\u003ch2\u003eL-Glutathione from Vit4ever\u003c\/h2\u003e\n\u003cp\u003e\u003cstrong\u003eL-glutathione\u003c\/strong\u003e is a molecule found in every cell of your body. It consists of three amino acids linked together: glutamic acid, cysteine, and glycine. Vit4ever supplies this tripeptide in its reduced form, with 500 mg per capsule, in a vegetable shell without further additives. A jar contains 120 capsules, enough for four months at one capsule per day. What many people don't know: glutathione is produced by your body itself, but production varies from cell to cell and from person to person.\u003c\/p\u003e\n\u003ch3\u003eWhat glutathione precisely is\u003c\/h3\u003e\n\u003cp\u003eChemically, glutathione is a tripeptide, a short chain of three amino acids. This distinguishes it from most supplements, which consist of a single amino acid or a vitamin. The molecule occurs naturally in almost every body cell, with the highest concentrations in the liver. In food, it is found in fresh meat, avocado, and certain vegetables, although some of it breaks down during cooking or heating. A supplement provides you with a fixed amount, regardless of what's on your plate. The structure of the molecule also determines how it behaves in the cell: the sulfur group in cysteine is the reactive component with which the molecule can chemically react with other substances in the cell. Researchers call this a thiol group, a chemical name for a sulfur atom with an attached hydrogen atom. This group is why glutathione so often appears in laboratory research: the molecule is chemically reactive and easily forms bonds with other substances.\u003c\/p\u003e\n\u003ch3\u003eThe difference between reduced and oxidized\u003c\/h3\u003e\n\u003cp\u003eGlutathione exists in two forms: reduced (abbreviated GSH) and oxidized (GSSG). The difference lies in a chemical bond between two glutathione molecules. In the reduced form, that sulfur atom is free; in the oxidized form, two molecules are linked together via that sulfur group. In body cells, glutathione typically occurs predominantly in the reduced form. Vit4ever therefore deliberately chooses GSH, the form closest to the natural cell form. Each capsule delivers a fixed 500 mg, so you don't have to measure and know exactly what you're getting. The difference between the two forms seems technical but is fundamentally simple: it's a matter of an extra or missing hydrogen atom at that one sulfur spot in the molecule.\u003c\/p\u003e\n\u003ch3\u003eVegan and without unnecessary additives\u003c\/h3\u003e\n\u003cp\u003eThe capsule consists of two parts: the glutathione itself and a shell of hydroxypropylmethylcellulose, a plant-based substance that serves as a substitute for animal gelatin. It contains no magnesium stearate, coloring, or filler. This keeps the label short and clear. The product is also free of gluten and lactose, making it suitable for people who avoid these substances for other reasons. Vit4ever has every produced batch independently tested in a laboratory, so that the amount of glutathione in the jar matches what is stated on the packaging. This is not self-evident: glutathione is a molecule that is sensitive to oxidation, meaning it can gradually convert from the reduced to the oxidized form during storage. Good packaging and limited exposure to air and light play a role in this.\u003c\/p\u003e\n\u003ch3\u003ePractical for daily use\u003c\/h3\u003e\n\u003cp\u003eYou take one capsule per day, preferably with a glass of water with a meal. The capsule is taste-neutral and normal in size, comparable to most other supplement capsules. With 120 pieces per jar, you get about four months of use, which reduces the chance that you will have to order a new jar halfway through. People interested in reduced glutathione often wonder why the reduced form is chosen over the oxidized. The answer lies in that cell structure: reduced glutathione is the form that predominates in cells. Another question that regularly comes up: why is the dosage per capsule fixed at 500 mg instead of a lower or higher amount? Vit4ever chooses a round, practical amount that suits a daily intake of a single capsule, without you needing multiple pieces per day to reach a meaningful amount.\u003c\/p\u003e\n\u003cp\u003eIn short: this is a simply composed supplement with L-glutathione in the reduced form, 500 mg per capsule, without superfluous additives and with a fixed dosage that easily fits into a daily routine. The combination of a short ingredient list and laboratory control per batch makes it easy for users to see exactly what is in the capsule.\u003c\/p\u003e","brand":"Vit4ever","offers":[{"title":"Default Title","offer_id":43788750618844,"sku":"vit4-449","price":24.9,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0609\/9006\/2812\/files\/vit4ever-l-glutathion-vit4ever-1.jpg?v=1793623873"},{"product_id":"glutathion-met-silymarine-nac-en-lola","title":"Glutathione with Silymarin, NAC and LOLA | 60 Capsules | Osavi","description":"\u003ch2\u003eGlutathione with Silymarin, NAC and LOLA from Osavi\u003c\/h2\u003e\n\u003cp\u003eThis Osavi supplement combines four ingredients. The main ingredient is \u003cstrong\u003ereduced L-glutathione\u003c\/strong\u003e, the reduced form of glutathione. It also contains N-acetyl-L-cysteine (NAC), L-ornithine L-aspartate (LOLA) and concentrated milk thistle extract. Each daily dose of two capsules provides 250 mg of glutathione, 250 mg of LOLA, 190 mg of NAC and 125 mg of milk thistle extract. The bottle contains 60 capsules, which is enough for about two months at the recommended daily dose of two capsules.\u003c\/p\u003e\n\u003ch3\u003eWhat reduced L-glutathione is exactly\u003c\/h3\u003e\n\u003cp\u003eGlutathione is a substance that your body produces itself. It consists of three amino acids: glutamate, cysteine and glycine. Together they form a small protein, a tripeptide. What many people do not know is that glutathione exists in two forms. The reduced form is abbreviated as GSH. This product contains reduced L-glutathione. In addition to glutathione, the formula also contains NAC, more about that below.\u003c\/p\u003e\n\u003ch3\u003eNAC: N-acetyl-L-cysteine\u003c\/h3\u003e\n\u003cp\u003eN-acetyl-L-cysteine, or NAC for short, is an acetylated form of the amino acid cysteine. Cysteine is one of the three amino acids that make up glutathione. With 190 mg per daily dose, NAC is on the modest side in this product compared to standalone NAC supplements, which often contain 600 mg or more per serving.\u003c\/p\u003e\n\u003ch3\u003eLOLA: L-ornithine L-aspartate\u003c\/h3\u003e\n\u003cp\u003eLOLA stands for L-ornithine L-aspartate, a combination of two amino acids. Ornithine and aspartate are amino acids that are also found in high-protein foods. Each daily dose of this product contains 250 mg of LOLA.\u003c\/p\u003e\n\u003ch3\u003eMilk thistle extract with silymarin\u003c\/h3\u003e\n\u003cp\u003eThe fourth ingredient is milk thistle seed extract, standardised to at least 80% silymarin. Silymarin is a complex of plant substances, including silybin and isosilybin. Milk thistle has long been used in European herbal tradition. Milk thistle supports normal liver function.* Milk thistle may also contribute to digestion.* The 20:1 extract means that twenty times as much plant material was used to make the extract. You therefore get a concentrated form. Each daily dose provides 125 mg of extract, of which at least 100 mg is silymarin.\u003c\/p\u003e\n\u003cp\u003eThis Osavi product combines four ingredients: reduced L-glutathione, NAC, LOLA and milk thistle extract. The capsules are vegan, gluten-free and free from soy and lactose. Anyone looking for glutathione, NAC, LOLA and milk thistle in one capsule will find a convenient combination here, albeit in modest doses per ingredient.\u003c\/p\u003e\n\u003cp\u003e*Health claim awaiting European approval.\u003c\/p\u003e","brand":"Osavi","offers":[{"title":"60 capsules","offer_id":53716599832914,"sku":"Osavi-038","price":23.9,"currency_code":"EUR","in_stock":true},{"title":"120 capsules","offer_id":53716599865682,"sku":"Osavi-045","price":26.9,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0609\/9006\/2812\/files\/GlutathionSilymarinNAC_LolaOsavi.jpg?v=1776179058"},{"product_id":"liposomale-glutathion-500mg","title":"Liposomal Glutathione 500mg | 60 Capsules | Osavi","description":"\u003ch2\u003eOsavi Liposomal Glutathione\u003c\/h2\u003e\n\u003cp\u003eThis Osavi supplement provides 500 mg of \u003cstrong\u003ereduced glutathione\u003c\/strong\u003e per daily dose of two capsules. What makes this product different from many other glutathione supplements? The liposomal technology. The glutathione is encapsulated in sunflower phospholipids (liposomal form).\u003c\/p\u003e\n\u003ch3\u003eWhat reduced glutathione actually is\u003c\/h3\u003e\n\u003cp\u003eGlutathione is a substance your body produces itself. It is a tripeptide, made up of three amino acids: glutamic acid, cysteine, and glycine. It is found in almost all your cells, with the highest concentration in the liver. In food, it is found in avocado, broccoli, asparagus, and garlic, among others, but usually in small amounts. There are two forms: reduced (GSH) and oxidized (GSSG). Osavi uses the reduced form in this product.\u003c\/p\u003e\n\u003ch3\u003eHow liposomal encapsulation works\u003c\/h3\u003e\n\u003cp\u003eOsavi uses Liposovit®-Glutathione, a dry liposomal form. Phospholipids from sunflower lecithin form small spheres, called liposomes, which surround the glutathione. These spheres are similar in structure to cell membranes. No soy, by the way, pure sunflower. This also makes it suitable for people who prefer to avoid soy.\u003c\/p\u003e\n\u003ch3\u003e500 mg per day in two capsules\u003c\/h3\u003e\n\u003cp\u003eOsavi opts for 500 mg of reduced glutathione per daily dose, divided over two capsules. Take two capsules per day, preferably after a meal. This way, you spread the intake over a fixed time of day.\u003c\/p\u003e\n\u003ch3\u003eInulin, capsule and allergens\u003c\/h3\u003e\n\u003cp\u003eIn addition to glutathione and phospholipids, this product also contains a small amount of inulin. Inulin is a soluble fiber that is usually extracted from chicory root. The amount here is deliberately small; it is mainly in the formulation as part of the carrier mix. The capsule itself is made of hydroxypropyl methylcellulose and is therefore completely plant-based. This makes the product suitable for vegans and vegetarians, and it is free from gluten, lactose, soy, and GMOs. A short, clear list of ingredients without unnecessary additives.\u003c\/p\u003e\n\u003cp\u003eWith 60 capsules in the bottle, you have a one-month supply when taking two capsules per day. A clear product with a short list of ingredients for those looking for reduced glutathione in liposomal form. In short, you know exactly what you are getting: 500 mg of reduced glutathione, neatly encapsulated in phospholipids.\u003c\/p\u003e","brand":"Osavi","offers":[{"title":"Default Title","offer_id":53197801292114,"sku":"Osavi-040","price":34.9,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0609\/9006\/2812\/files\/LiposomalGlutathionOsavi.jpg?v=1776248069"},{"product_id":"glutathion-met-mariadistel-alfa-liponzuur-500mg-now-foods","title":"Glutathione with Milk Thistle \u0026 Alpha-Lipoic Acid 500mg | 60 Capsules | NOW Foods","description":"\u003ch2\u003eGlutathione with Milk Thistle from NOW Foods\u003c\/h2\u003e\n\u003cp\u003eAre you looking for a supplement in which \u003cstrong\u003eglutathione\u003c\/strong\u003e is combined with milk thistle and alpha-lipoic acid? Then this capsule from NOW Foods may be of interest. Each capsule contains 500 mg of reduced glutathione, 100 mg of milk thistle extract and 50 mg of alpha-lipoic acid. One bottle contains 60 plant-based capsules. That is a two-month supply if you take one daily, as indicated on the label.\u003c\/p\u003e\n\u003ch3\u003eWhat glutathione actually is\u003c\/h3\u003e\n\u003cp\u003eGlutathione is a tripeptide (a small protein consisting of three amino acids). Those three building blocks are cysteine, glutamic acid and glycine. Your body produces it itself, mainly in the liver, and you can find it in almost every cell. What many people do not know is that glutathione exists in two forms. The reduced form (GSH) is the active variant that can donate electrons. As soon as that happens, it changes into the oxidized form (GSSG). Your cells then convert it back into the active form. This capsule contains the reduced form, so the variant your body uses itself. Each capsule contains 500 mg of glutathione.\u003c\/p\u003e\n\u003ch3\u003eMilk thistle and alpha-lipoic acid as companions\u003c\/h3\u003e\n\u003cp\u003eMilk thistle (Silybum marianum) is a species of thistle with purple flowers. You extract silymarin from the fruit and seeds, a group of plant substances called flavonolignans. The extract in this capsule is standardized to 80% silymarin, which amounts to 80 mg per capsule. This standardization means that every batch contains the same amount of silymarin. Milk thistle supports liver health*. And milk thistle helps maintain heart health*. In addition, each capsule contains 50 mg of alpha-lipoic acid. This is a sulfur-containing fatty acid that your body produces in small amounts in the mitochondria (the powerhouses of your cells). Alpha-lipoic acid dissolves in both water and fat.\u003c\/p\u003e\n\u003ch3\u003eWhy these three are together in one capsule\u003c\/h3\u003e\n\u003cp\u003eThe difference with a separate glutathione supplement lies in the combination. NOW Foods has combined glutathione, milk thistle and alpha-lipoic acid in one capsule. Good to know: the capsule is made of hypromellose (a plant-based cellulose), so it contains no gelatin. The recommendation is to take it on an empty stomach. Many people choose the time right after waking up, half an hour before breakfast.\u003c\/p\u003e\n\u003cp\u003eThis glutathione capsule is made in the United States, in a facility that operates according to GMP guidelines (Good Manufacturing Practice). NOW Foods tests raw materials and finished products in its own laboratories. Anyone looking for a glutathione supplement with a clear label and three recognizable substances has a straightforward formula here.\u003c\/p\u003e\n\u003cp\u003e*Health claim pending European approval.\u003c\/p\u003e","brand":"NOW Foods","offers":[{"title":"Default Title","offer_id":54816681591122,"sku":"Now-073","price":32.9,"currency_code":"EUR","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0609\/9006\/2812\/files\/glutathion-met-mariadistel-alfa-liponzuur-500mg-now-foods.jpg?v=1790166968"}],"url":"https:\/\/www.luto-supplements.nl\/en\/collections\/glutathion.oembed","provider":"LUTO Supplements","version":"1.0","type":"link"}