What is GABA?
GABA, short for gamma-aminobutyric acid, is a neurotransmitter in your nervous system. It acts as a brake: it makes nerve cells less likely to transmit a signal. Your body produces it itself from glutamate, with the help of vitamin B6.
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GABA is one of the best-known neurotransmitters in your brain. In these capsules, NOW Foods combines 500mg of GABA with 2mg of vitamin B6. The two go together, and you'll read why further on. The bottle is available with 100 or 200 plant-based capsules.
GABA stands for gamma-aminobutyric acid. It is an amino acid, but not a building block for proteins. Your body uses it as a neurotransmitter (a messenger substance between nerve cells). About a third of all nerve cells in your brain use GABA. It is also found in food, especially in fermented products such as kimchi, tempeh and some types of tea, and in sprouted brown rice. The name, by the way, says something about its structure. Gamma means that the amino group is at the third carbon position from the acid group, and butyric acid refers to the skeleton of four carbon atoms. Plants and bacteria also produce it, and in plants it plays a role, among other things, in the response to stress such as drought and cold.
Your body produces GABA itself from glutamate. An enzyme is needed for this, glutamate decarboxylase, abbreviated GAD. And that enzyme cannot function without the active form of vitamin B6 as a cofactor. Without B6, that conversion therefore stalls. That is where the combination comes into play. Vitamin B6 contributes to the normal functioning of the nervous system. Vitamin B6 also contributes to normal psychological function. And vitamin B6 contributes to the reduction of tiredness and fatigue. With 2mg per capsule, you get 143 percent of the reference intake, well within the safe margin.
NOW's advice is to take the capsule on an empty stomach, with water or juice. Then GABA does not compete with other amino acids from your meal for absorption in the intestine.
Choose your size: the bottle with 100 capsules is a nice size to try out whether GABA fits into your daily routine, the bottle with 200 capsules is convenient if you use it daily. The capsules are made of cellulose, without gelatin, and are not produced with gluten, soy, milk or egg. NOW makes and tests them in their own GMP factories in the United States.
One capsule contains 500mg gamma-aminobutyric acid.
Your body needs vitamin B6 to produce GABA itself. Vitamin B6 contributes to the normal functioning of the nervous system.
With two capsules per day, you have a 50- or 100-day supply. The small bottle is convenient if you are trying GABA for the first time, the large one if you use it daily.
No gelatin and not produced with gluten, soy, corn, milk or egg. Suitable for vegetarians.
* Percentage van de referentie inname volgens Verordening (EU) Nr. 1169/2011.
** Reference intake unknown.
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GABA, short for gamma-aminobutyric acid, is a neurotransmitter in your nervous system. It acts as a brake: it makes nerve cells less likely to transmit a signal. Your body produces it itself from glutamate, with the help of vitamin B6.
NOW recommends one capsule two to three times daily as needed. This amounts to 1000 to 1500mg of GABA and 4 to 6mg of vitamin B6 per day. Do not exceed the recommended daily dose.
On an empty stomach, with water or juice. This way, GABA does not compete with proteins from your meal. You choose the time yourself; many people spread the capsules throughout the day.
That is not yet well established. The blood-brain barrier does not let everything through, and studies show mixed results. Therefore, we cannot claim any effect for GABA itself. What is certain: vitamin B6 contributes to normal psychological function.
Because vitamin B6 is the cofactor for the enzyme that converts glutamate into GABA. Without B6, your body cannot produce GABA on its own. Vitamin B6 also contributes to normal energy-yielding metabolism and to the reduction of tiredness and fatigue.
This variant contains 500mg GABA plus 2mg vitamin B6 per capsule. GABA 750mg from NOW contains only GABA, but more per capsule. If you want the B6 included, choose this one. If you already take a B-complex, the pure 750mg version might suit you better.