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If you already use tudca, or are considering it, this question will sooner or later come up: take it on its own or in combination? Applied Nutrition chose the latter. Three capsules together deliver 800mg of tauroursodeoxycholic acid and 900mg of N-acetylcysteine, better known as NAC. Everything is in a plant-based capsule, made in the United Kingdom. A bottle of 90 capsules is enough for 30 days.
Tudca stands for tauroursodeoxycholic acid. That is a bile acid, a substance your liver produces itself and sends to your intestines via bile to digest fats. It is formed when ursodeoxycholic acid binds to the amino acid taurine. Because of this binding, it dissolves well in water, better than most other bile acids. What many people do not know: naturally, there is only a very small amount of it in your bile. A tudca supplement therefore contains a much larger amount than your body produces itself.
NAC is a modified form of the amino acid cysteine. It has an extra acetyl group attached, making the molecule more stable than free cysteine. Tudca is a bile acid, NAC an amino acid derivative: two different substances. Many users took these two substances for years as separate bottles alongside each other. With this tudca NAC combination, you have them in one product. Good to know: NAC has a slightly sulfurous smell on its own. You will smell that when you open the bottle, and that is normal.
Most separate tudca capsules contain 250mg or 500mg each. With 800mg per daily dose, this product is therefore at the top end of what you will find in stores, without having to swallow a handful of capsules. For NAC, there is a clear Dutch benchmark. The RIVM has assessed the safety of N-acetylcysteine in food supplements and lists 1200mg per day as the maximum amount for adults. The 900mg in this formula remains well below that. In practice, this means: if you take this product, you no longer need a separate NAC supplement. In fact, we advise against it, because you will more quickly exceed that limit.
In addition to tudca and NAC, the capsule contains few extras. It contains microcrystalline cellulose as a filler and a small amount of magnesium stearate, so that the powder does not stick to the machines. The capsule shell is made of hydroxypropyl methylcellulose (HPMC, a plant-based alternative to gelatin). Therefore, these tudca capsules are suitable for vegetarians and vegans, and the product carries a halal certificate. Applied Nutrition has the capsules produced in a factory with ISO 22000, BRC, and GMP certification and places the Tested for Athletes logo on the packaging.
In short: this is not pure tudca, but a deliberate combination of a bile acid and an amino acid derivative in one bottle. If you only want tauroursodeoxycholic acid, a separate product is a better fit. If you are specifically looking for these two together, in a fixed ratio and in a plant-based capsule, then this is the formula made for that.
Three capsules together provide 800mg tauroursodeoxycholic acid and 900mg N-acetylcysteine. This keeps the NAC below the 1200mg per day that the RIVM lists as the maximum for adults.
TUDCA and NAC are two different substances, combined here in a fixed ratio, so you don't need two separate jars.
The capsule shell is made of hydroxypropyl methylcellulose instead of gelatin. The product is suitable for vegans and is halal certified.
With 3 capsules per day, one bottle lasts a full month. Made in the United Kingdom in a factory with ISO 22000, BRC, and GMP certification.
* Percentage van de referentie inname volgens Verordening (EU) Nr. 1169/2011.
** Reference intake unknown.
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Tudca is tauroursodeoxycholic acid, a bile acid that your body produces itself in small amounts. It is formed when ursodeoxycholic acid binds to the amino acid taurine. This makes it highly soluble in water. In supplements, a purified form is used in a much larger quantity than naturally occurs in your bile.
Yes, and they are already combined in this product. Three capsules provide 800mg of tudca and 900mg of NAC. Do not take an additional NAC supplement or combine it with the mucolytic medication acetylcysteine without consulting your doctor. The RIVM states that 1200mg of NAC per day is the maximum for adults.
With the recommended daily dose of 3 capsules, you get 800mg of tudca. Applied Nutrition advises taking the capsules in the morning, 30 to 45 minutes before breakfast. A jar of 90 capsules will last exactly 30 days this way.
This is due to the NAC. N-acetylcysteine contains a sulfur group and therefore naturally has a distinctive odor. The manufacturer states that this odor is normal and does not reflect the quality. Close the container tightly after use to keep the odor contained.
NAC stands for N-acetylcysteine: the amino acid cysteine with an extra acetyl group. That acetyl group makes NAC more stable than free cysteine. Per daily dose of 3 capsules you get 900mg NAC.
The difference lies in the composition. Tudca on its own, such as German Elite Nutrition's TUDCA 1000mg, contains only the bile acid (in that case with some black pepper extract). Applied Nutrition's Tudca + NAC combines 800mg of tudca with 900mg of NAC, an amino acid derivative. If you only want tudca in a high dosage, choose a separate product. If you want both substances in one container, this combination is more convenient.
